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Human AGTR1 Stable Cell Line-CHO

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Cat.No.
CSC-RG0802
Background
Two receptors for angiotensin II have been identified, AT1 and AT2 receptors. AT1 receptor antagonists have been shown to lower arterial blood pressure, reduce cardiac load, inhibit sympathetic activity and prevent cardiovascular hypertrophy.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Stability
Functional response observed for at least 8 passages
Ship
Dry ice
Gene Information
Official Symbol
AGTR1
Synonyms
AGTR1; angiotensin II receptor, type 1; AGTR1B, angiotensin receptor 1B; type-1 angiotensin II receptor; AG2S; AGTR1A; AT1; AT1B; AT2R1; AT2R1A; AT2R1B; HAT1R; AT1AR; AT1BR; angiotensin receptor 1; angiotensin receptor 1B; angiotensin II type-1 receptor; type-1B angiotensin II receptor; AT1R; AGTR1B;
Gene ID
MIM
UniProt ID
P30556
Chromosome Location
3q24
Pathway
ACE Inhibitor Pathway, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Arf6 signaling events, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem;
Function
G-protein coupled receptor activity; acetyltransferase activator activity; angiotensin type I receptor activity; angiotensin type I receptor activity; angiotensin type II receptor activity; bradykinin receptor binding; protein binding; protein heterodimerization activity; receptor activity; signal transducer activity;

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