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Human ADRB3 Validated Stable Cell Line-CHO

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Cat.No.
CSC-RG1124
Background
The beta3-adrenoceptor is also known as the atypical betaadrenoceptor. It was considered as a potential anti-obesity target by increasing energy expenditure and lipolysis in brown and white adipose tissues of rodents. The functional receptor has been demonstrated in a variety of other tissues including blood vessel, gastrointestinal tract, muscle, and retinal endothelial cells,
and its agonist evokes relaxation in some of these tissues such as gall bladder, stomach, small intestine, prostate, colon and bladder.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
ADRB3
Synonyms
ADRB3; adrenergic, beta-3-, receptor; beta-3 adrenergic receptor; beta-3 adrenoceptor; beta-3 adrenoreceptor; BETA3AR; FLJ99960;
Gene ID
MIM
UniProt ID
P13945
Chromosome Location
8p12
Pathway
Adrenoceptors, organism-specific biosystem; Amine ligand-binding receptors, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Endocytosis, organism-specific biosystem;
Function
G-protein coupled receptor activity; beta-3 adrenergic receptor binding; beta-adrenergic receptor activity; beta3-adrenergic receptor activity; epinephrine binding; contributes_to norepinephrine binding; protein binding; protein homodimerization activity; receptor activity; signal transducer activity;

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