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Human ADRA2C Stable Cell Line-CHO

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Cat.No.
CSC-RG0799
Background
Three alpha2-adrenoceptors have been cloned, and are designated alpha2a, alpha2b and alpha2c. All three receptors are activated by norepinephrine and all three are coupled via Gi to adenylate cyclase. The alpha2c adrenergic receptor is widely distributed in the CNS and in lung and mediates vasoconstriction and modulation of neurotransmission.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Stability
12 passages (6 weeks of continuous culture)
Ship
Dry ice
Gene Information
Official Symbol
ADRA2C
Synonyms
ADRA2C; adrenergic, alpha-2C-, receptor; ADRA2L2, ADRA2RL2; alpha-2C adrenergic receptor; ADRARL2; alpha-2CAR; alpha2-AR-C4; alpha-2C adrenoceptor; alpha-2C adrenoreceptor; alpha-2C-adrenergic receptor; alpha-2 adrenergic receptor subtype C4; ADRA2L2; ADRA2RL2; ALPHA2CAR;
Gene ID
UniProt ID
P18825
Chromosome Location
4p16.3
Pathway
Adrenaline signalling through Alpha-2 adrenergic receptor, organism-specific biosystem; Adrenoceptors, organism-specific biosystem; Amine ligand-binding receptors, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; G alpha (z) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
Function
G-protein coupled receptor activity; adrenergic receptor activity; alpha-2A adrenergic receptor binding; alpha2-adrenergic receptor activity; epinephrine binding; protein binding; protein heterodimerization activity; protein homodimerization activity; receptor activity; signal transducer activity;

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