Human ADRA1A Stable Cell Line-CHO-K1

Name: Human ADRA1A Stable Cell Line-CHO-K1
SKU: CSC-RG0794
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RG0794

Host Cell : CHO-K1 Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RG0794
Background	Alpha-1 adrenergic receptors are widely distributed and mediate a variety of functions including smooth muscle contraction, cardiac stimulation, cellular proliferation, apoptosis and activation of hepatic gluconeogenesis and clycogenolysis. Three distinct alpha-1 adrenergic receptors have been identified and are known as alpha-1a, alpha-1b, and alpha-1c receptors.
Target Gene	ADRA1A
Gene Species	Homo sapiens (Human)
Abbr	CHO-HuADRA1A
Alias	ADRA1A, ADRA1C, ADRA1L1, ALPHA1AAR
Host Cell	CHO-K1
Host Cell Species	Cricetulus griseus (Chinese hamster)
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Adherent
Morphology	Epithelial-like

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ADRA1A adrenoceptor alpha 1A [ Homo sapiens ]
Gene Symbol	ADRA1A
Synonyms	ADRA1C; ADRA1L1; ALPHA1AAR
Gene Description	adrenergic, alpha-1A-, receptor
GeneID	148
Uni ProtID	P35348
mRNA Refseq	NM_000680.2
Protein Refseq	NP_000671.2
Chromosome Location	8p21.2
Function	alpha1-adrenergic receptor activity; alpha1-adrenergic receptor activity; alpha1-adrenergic receptor activity; protein heterodimerization activity;
Pathway	AMPK signaling, organism-specific biosystem; Adrenoceptors, organism-specific biosystem; Amine ligand-binding receptors, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem;
MIM	104221

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