Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : SHH242290
| Cat. No. | SHH242290 |
| Description | The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells. |
| Gene Abbr | ATM |
| Gene Name | Atm ataxia telangiectasia mutated homolog (human) [ Mus musculus ] |
| Species | Rat |
| Report Gene | GFP |
| Storage | The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C. |
| Gene Name | Atm ataxia telangiectasia mutated homolog (human) [ Mus musculus ] |
| Gene Symbol | Atm |
| Synonyms | AI256621; C030026E19Rik |
| Gene Description | ataxia telangiectasia mutated homolog (human) |
| GeneID | 11920 |
| Uni ProtID | Q62388 |
| mRNA Refseq | NM_007499.2 |
| Protein Refseq | NP_031525.2 |
| Chromosome Location | 9 C-D; 9 30.0 cM |
| Function | 1-phosphatidylinositol-3-kinase activity; ATP binding; DNA binding; DNA-dependent protein kinase activity; histone serine kinase activity; kinase activity; nucleotide binding; phosphotransferase activity, alcohol group as acceptor; protein N-terminus binding; protein binding; protein complex binding; protein dimerization activity; protein kinase activity; protein kinase activity; protein serine/threonine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups; |
| Pathway | ATM mediated phosphorylation of repair proteins, organism-specific biosystem; ATM mediated response to DNA double-strand break, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis signaling pathway, organism-specific biosystem; Autodegradation of the E3 ubiquitin ligase COP1, organism-specific biosystem; BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; |
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