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shRNA set against Rat ATM (NM_001106821.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH242290

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Gene Information

Cat. No. SHH242290
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr ATM
Gene Name Atm ataxia telangiectasia mutated homolog (human) [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Atm ataxia telangiectasia mutated homolog (human) [ Mus musculus ]
Gene Symbol Atm
Synonyms AI256621; C030026E19Rik
Gene Description ataxia telangiectasia mutated homolog (human)
GeneID 11920
Uni ProtID Q62388
mRNA Refseq NM_007499.2
Protein Refseq NP_031525.2
Chromosome Location 9 C-D; 9 30.0 cM
Function 1-phosphatidylinositol-3-kinase activity; ATP binding; DNA binding; DNA-dependent protein kinase activity; histone serine kinase activity; kinase activity; nucleotide binding; phosphotransferase activity, alcohol group as acceptor; protein N-terminus binding; protein binding; protein complex binding; protein dimerization activity; protein kinase activity; protein kinase activity; protein serine/threonine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups;
Pathway ATM mediated phosphorylation of repair proteins, organism-specific biosystem; ATM mediated response to DNA double-strand break, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis signaling pathway, organism-specific biosystem; Autodegradation of the E3 ubiquitin ligase COP1, organism-specific biosystem; BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem;
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