shRNA set against Mouse Atm(NM_007499.2)

Name: shRNA set against Mouse Atm(NM_007499.2)
SKU: SHG080529
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHG080529

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Product Information

Gene Information

Cat. No.	SHG080529
Description	Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr	Atm
Gene Name	Atm ataxia telangiectasia mutated homolog (human) [ Mus musculus ]
Species	Mouse
Report Gene	eGFP
Content	Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence.
Promoter	H1
Selection	Puromycin
Format	5 μg purified plasmid
Unit Size	5 μg
Sequence	The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Shipping	Typically ships in 2-3 weeks

Gene Name	Atm ataxia telangiectasia mutated homolog (human) [ Mus musculus ]
Gene Symbol	Atm
Synonyms	AI256621; C030026E19Rik
Gene Description	ataxia telangiectasia mutated homolog (human)
GeneID	11920
Uni ProtID	Q62388
mRNA Refseq	NM_007499.2
Protein Refseq	NP_031525.2
Chromosome Location	9 C-D; 9 30.0 cM
Function	1-phosphatidylinositol-3-kinase activity; ATP binding; DNA binding; DNA-dependent protein kinase activity; histone serine kinase activity; kinase activity; nucleotide binding; phosphotransferase activity, alcohol group as acceptor; protein N-terminus binding; protein binding; protein complex binding; protein dimerization activity; protein kinase activity; protein kinase activity; protein serine/threonine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups;
Pathway	ATM mediated phosphorylation of repair proteins, organism-specific biosystem; ATM mediated response to DNA double-strand break, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis signaling pathway, organism-specific biosystem; Autodegradation of the E3 ubiquitin ligase COP1, organism-specific biosystem; BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem;

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