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Human ATM ORF Clone(NM_000051.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR277773

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Gene Information

Cat. No. CDCR277773
Product Type ORF Clone
Gene Abbr ATM
Gene Name ATM ataxia telangiectasia mutated [ Homo sapiens ]
Species Human
Tag C-terminal Myc-DDK
ORF Size 9171 bp
Vector pCMV6-Entry
Gene Name ATM ataxia telangiectasia mutated [ Homo sapiens ]
Gene Symbol ATM
Synonyms AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1
Gene Description ataxia telangiectasia mutated (includes complementation groups A, C and D)
GeneID 472
Uni ProtID Q13315
mRNA Refseq NM_000051.3
Protein Refseq NP_000042.3
Chromosome Location 11q22-q23
Function 1-phosphatidylinositol-3-kinase activity; ATP binding; DNA binding; DNA-dependent protein kinase activity; histone serine kinase activity; protein N-terminus binding; protein binding; protein complex binding; protein dimerization activity; protein serine/threonine kinase activity;
Pathway ATM mediated phosphorylation of repair proteins, organism-specific biosystem; ATM mediated response to DNA double-strand break, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Autodegradation of the E3 ubiquitin ligase COP1, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem;
MIM 607585
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