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RABV-N2C(G)-ΔG-EGFP

For research use only. Not intended for any clinical use.

Cat. No. :   VNTR-5

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Virus Particles Information

Cat. No. VNTR-5
Description Rabies virus CVS-N2c strain-based retrograde non-synaptic tracer with the native G gene replaced by the N2c glycoprotein (N2c-G) and the EGFP reporter inserted. The CVS-N2c strain exhibits reduced neuronal toxicity and enhanced transsynaptic transfer efficiency (10-20-fold higher than SAD-B19). Pseudotyped with N2c-G on the surface, this virus enables highly efficient retrograde infection of projection neurons through axon terminals for single-cell labeling of input networks (no transsynaptic spread, used to label directly projecting neurons only).
Product Type Rabies virus
Reporter EGFP (Enhanced Green Fluorescent Protein)
Synaptic Transmission Non-synaptic (single-cell labeling of input neurons)
Applications
  1. Retrograde non-synaptic (single-cell) labeling of projection neurons via axon terminal uptake
  2. High-efficiency retrograde labeling of input neurons with reduced toxicity
  3. Morphological analysis of projection neurons
  4. Functional dissection of inputs with optogenetic/calcium sensors in N2c-G pseudotyped RV systems.
Size Custom
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Dry ice
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