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rAAV-EF1a-DIO-oG

For research use only. Not intended for any clinical use.

Cat. No. :   RABVH-42

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Virus Particles Information

Cat. No. RABVH-42
Description Cre-dependent AAV helper expressing a codon-optimized rabies glycoprotein (oG) under EF1a. The optimized coding sequence enhances glycoprotein expression in Cre-positive neurons, efficiently complementing G-deleted rabies virus and enabling a single retrograde transsynaptic step. Combined with a TVA helper, it supports Cre-specific monosynaptic input mapping.
Product Type Adeno-associated virus
Expression Mechanism Cre-dependent
Helper Function AAV helper expressing codon-optimized rabies glycoprotein (oG) under Cre-dependent control
Applications
  1. Co-injection with TVA helper AAV and RV-EnvA-ΔG for Cre-dependent monosynaptic retrograde tracing
  2. oG (codon-optimized G) for enhanced trans-complementation efficiency
  3. DIO restricts to Cre+ populations
  4. Mapping direct presynaptic inputs to Cre-defined populations
  5. Enhanced efficiency vs. native RVG
Promoter Broad-spectrum Promoter
Size Custom
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Dry ice
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