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rAAV-CAG-FLEX-TVA(E66T)

For research use only. Not intended for any clinical use.

Cat. No. :   RABVH-11

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Virus Particles Information

Cat. No. RABVH-11
Description Cre-dependent AAV helper expressing only the low-affinity TVA(E66T) receptor under CAG in a FLEX configuration, without any fluorescent reporter. After Cre recombination the targeted neurons become selectively permissive to EnvA-pseudotyped G-deleted rabies virus. This reporter-free design avoids spectral occupancy, freeing all fluorescence channels for the rabies tracer and additional circuit labels.
Product Type Adeno-associated virus
Helper Function AAV helper expressing low-affinity TVA(E66T) under Cre-dependent FLEX switch (no reporter)
Applications
  1. Co-injection with RV-EnvA-ΔG-mCherry or -EGFP for Cre-dependent monosynaptic retrograde tracing
  2. CAG promoter for strong broad expression
  3. TVA(E66T) provides reduced-affinity receptor for cleaner starter cell specificity
  4. FLEX switch restricts expression to Cre+ populations
  5. No fluorescent reporter — relies on RV-encoded reporter for starter cell visualization
  6. Use when starter cell visualization is provided by the rabies virus itself
Promoter Broad-spectrum Promoter
Size Custom
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Dry ice
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