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Recombinant Human MSLN (C-Fc)

For research use only. Not intended for any clinical use.

Cat. No. :   RP00520 Tag :   C-Fc

Expressed Region :   Leu37-Arg286 Expression System :   Human Cell

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Product Information

Gene Information

Cat. No. RP00520
Description Recombinant Human MSLN (C-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Leu37-Arg286 with a Fc tag at the C terminus.
Species Human
Tag C-Fc
Mol Weight 53.9 KDa
Conjugate Unconjugated
Format Powder
Expressed Region Leu37-Arg286
Expression System Human Cell
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity >95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Endotoxin Level < 1 EU/µg of protein by LAL method
Storage Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Target Gene MSLN
Background This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Synonyms Megakaryocyte potentiating factor; mesothelin; Pre-pro-megakaryocyte-potentiating factor; soluble MPF mesothelin related protein; CAK1; MPF; MSLN; SMR; CAK1; CAK1 antigen
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