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Rat Msln ORF Clone(NM_031658.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR379813

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Gene Information

Cat. No. CDCR379813
Product Type ORF Clone
Gene Abbr Msln
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1878 bp
Vector pCMV6-Entry
Target Gene MSLN
Background This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
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