Recombinant Human MSLN (C-Fc)

Name: Recombinant Human MSLN (C-Fc)
SKU: RP00519
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00519 Tag : C-Fc

Expressed Region : Glu296-Ser598 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00519
Description	Recombinant Human MSLN (C-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Glu296-Ser598 with a Fc tag at the C terminus.
Species	Human
Tag	C-Fc
Mol Weight	61 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Glu296-Ser598
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	MSLN
Background	This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Synonyms	Megakaryocyte potentiating factor; mesothelin; Pre-pro-megakaryocyte-potentiating factor; soluble MPF mesothelin related protein; CAK1; MPF; MSLN; SMR; CAK1; CAK1 antigen

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