Recombinant Cavia porcellus CTLA-4 (C-6His)

Name: Recombinant Cavia porcellus CTLA-4 (C-6His)
SKU: RP00415
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00415 Tag : C-6His

Expressed Region : Ala37-Asp161 Expression System : P.Pichia

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Product Information

Gene Information

Cat. No.	RP00415
Description	The Recombinant Cavia porcellus CTLA-4 (C-6His) is produced in our P.Pichia expression system. The amino acid region expressed is Ala37-Asp161 with a 6His tag at the C terminus.
Species	Cavia porcellus
Tag	C-6His
Mol Weight	16-35 KDa
Conjugate	Unconjugated
Format	Liquid
Expressed Region	Ala37-Asp161
Expression System	P.Pichia
Formulation	Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.

Target Gene	CTLA4
Background	This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Synonyms	Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4

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