ODN 2138

Name: ODN 2138
SKU: CGON-15
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CGON-15

Inquire for Price

Product Information

Cat. No.	CGON-15
Description	CpG oligodeoxynucleotides (or CpG ODNs) are synthetic oligonucleotides that contain unmethylated CpG motifs. CpG ODN can bind to and activate a Toll-like receptor 9 (TLR9) and leading to strong immunostimulatory effects. So far 3 major classes of CpG ODNs have been identified, based on their structural and biological characteristics, and are designated Type A, Type B, and Type C. Type A ODNs, which feature a central palindromic CpG-containing phosphodiester (PO) structure followed by a phosphorothioate (PS) homopolymeric G-stretch, are robust inducers of interferon-α (IFN-α) production and dendritic cell maturation. Type B ODNs, in contrast, contain a full phosphorothioate backbone with one or more CpG dinucleotides. They strongly activate B cells but stimulate weakly IFN-α secretion. Type C ODNs, combine the properties of both Type A and B, and are characterized by their complete PS backbone and palindromic CpG-containing motifs. Type C ODNs induce strong IFN-α production from pDC and B cell stimulation. ODN 2138 can be used as a control for ODN 1826.
Features	• Classification: Type B control • Product format: Lyophilized product • Sequence: 5'-tccatgagcttcctgagctt-3' (lower case letters are phosphorothioate) • Specificity: Control for ODN 1826
Storage	Store lyophilized product at -20°C. Upon reconstitution, aliquots should be stored at -20°C and are stable for 6 months. Avoid repeated freeze-thaw cycles.

Quick Inquiry

Q & A

Customer Reviews

Customer Q&As

Is the product ODN 2138 solid?

A: The product form of ODN 2138 is lyophilized.

What is the sequence of ODN 2138?

A: The sequence of ODN 2138 is 5'-tccatgagcttcctgagctt-3' (lowercase letters represent thiophosphate).

What should be noted when storing ODN 2138?

A: It's important to avoid repeated freeze-thaw cycles.

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *