Human TNFSF15 Stable Cell Line - HEK293T

Name: Human TNFSF15 Stable Cell Line - HEK293T
SKU: CSC-RO0525
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RO0525

Host Cell : HEK293T Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RO0525
Description	This cell line is derived from HEK293T and is engineered to stably overexpress Human TNFSF15.
Target Gene	TNFSF15
Gene Species	Homo sapiens (Human)
Host Cell	HEK293T
Host Cell Species	Homo sapiens (Human)
Applications	1. Studying the interactions between immune cells and cancer cells 2. Studying the mechanisms of resistance to immune checkpoint blockade 3. High-throughput screening 4. Drug target validation
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 [ Homo sapiens ]
Gene Symbol	TNFSF15
Synonyms	TL1; TL1A; VEGI; VEGI192A
Gene ID	9966
Uni Prot ID	O95150
m RNA Refseq	NM_001204344.1
Protein Refseq	NP_001191273.1
Chromosome Location	9q32
Function	cytokine activity; death receptor binding; receptor binding; tumor necrosis factor receptor binding;
Pathway	Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Senescence and Autophagy, organism-specific biosystem;
MIM	604052

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