Recombinant Human TNFSF15 (N-6His)

Name: Recombinant Human TNFSF15 (N-6His)
SKU: RP00569
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00569 Tag : N-6His

Expressed Region : Leu72-Leu251 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00569
Description	Recombinant Human TNFSF15 (N-6His) is produced in our Human Cell expression system. The amino acid region expressed is Leu72-Leu251 with a 6His tag at the N terminus.
Species	Human
Tag	N-6His
Mol Weight	21.3 KDa
Conjugate	Unconjugated
Format	Liquid
Expressed Region	Leu72-Leu251
Expression System	Human Cell
Formulation	Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.

Target Gene	TNFSF15
Synonyms	Tumor Necrosis Factor Ligand Superfamily Member 15; TNF Ligand-Related Molecule 1; Vascular Endothelial Cell Growth Inhibitor; TNFSF15; TL1; VEGI; TL1A

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Customer Reviews

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene.

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