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Human ENTPD1 Stable Cell Line - CHO-K1

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-RO0920

Host Cell :   CHO-K1 Size :   >1x106 frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No. CSC-RO0920
Description This cell line is engineered to stably overexpress human ENTPD1 (also named as CD39).
Target Gene ENTPD1
Gene Species Homo sapiens (Human)
Host Cell CHO-K1
Host Cell Species Cricetulus griseus (Chinese hamster)
Applications

1. Studying the interactions between immune cells and cancer cells

2. Studying the mechanisms of resistance to immune checkpoint blockade

3. High-throughput screening

4. Drug target validation

Size >1x106 frozen cells/vial
Stability Validated for at least 10 passages
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid nitrogen
Shipping Dry ice
Revival Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 [ Homo sapiens ]
Gene Symbol ENTPD1
Synonyms ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1; CD39; ATPDase; NTPDase 1; CD39 antigen; ecto-apyrase; ecto-ATPase 1; ecto-ATPDase 1; ecto-ATP diphosphohydrolase 1; lymphoid cell activation antigen; NTPDase-1; FLJ40921; FLJ40959; DKFZp686D194; DKFZp686I093;
Gene ID 953
Uni Prot ID P49961
m RNA Refseq BC047664
Chromosome Location 10q23.1-q24.1
Function ATP binding; hydrolase activity; nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; nucleotide binding;
Pathway Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; Pyrimidine metabolism, organism-specific biosystem; Pyrimidine metabolism, conserved biosystem;
MIM 601752
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