Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : VNTH-5
| Cat. No. | VNTH-5 |
| Description | Cre-conditional, replication-incompetent anterograde monosynaptic HSV-1 H129 tracer. The TK (UL23) gene is replaced by a Cre-activated expression cassette containing a LoxP-Stop-LoxP (LSL) element placed between the strong synthetic CAG promoter and the tdTomato gene. Without Cre, the floxed STOP blocks expression and no tdTomato is produced. In combination with Cre-expressing animals (or local AAV-Cre delivery) and an AAV-DIO-TK helper virus, the STOP is excised specifically in Cre+ starter neurons, allowing monosynaptic anterograde spread to label Cre+ starter neurons and their directly connected postsynaptic neurons. |
| Product Type | Herpes simplex virus |
| Reporter | tdTomato |
| Synaptic Transmission | Mono-synaptic (single-step, with AAV-DIO-TK helper) |
| TKStatus | TK-deleted (ΔTK, replication-incompetent alone) |
| Applications |
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| Size | Custom |
| Storage | Store at -80℃. Avoid multiple freeze/thaw cycles. |
| Shipping | Dry ice |
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