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HSV1-HBEGFP

For research use only. Not intended for any clinical use.

Cat. No. :   VNTH-3

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Virus Particles Information

Cat. No. VNTH-3
Description HSV-1 H129-based high-brightness anterograde polysynaptic tracer built with a Trojan horse-like strategy. The H129 genome is engineered to incorporate AAV2 ITRs and an AAV2 Rep expression cassette together with a human ubiquitin C (hUbC) promoter-driven EGFP expression unit flanked by AAV ITRs, enabling amplification of the EGFP cassette via AAV replication in the HSV context. The resulting HBEGFP (high-brightness EGFP) tracer yields ~2-fold higher EGFP gene copy number and significantly stronger fluorescence than conventional H129-EGFP, producing robust anterograde multi-synaptic labeling of output neural circuits.
Product Type Herpes simplex virus
Reporter HBEGFP (High-Brightness EGFP via Trojan horse strategy)
Synaptic Transmission Multi-synaptic (Polysynaptic)
TKStatus Full-length TK (replication-competent)
Applications
  1. High-brightness anterograde multi-synaptic neuronal tracing
  2. Mapping distant brain-wide output networks that require strong fluorescent signal
  3. Visualization of fine neuronal morphology and dendritic structures
  4. Rapid neural circuit mapping with detection at earlier time points post-injection
  5. Dual-color experiments (paired with red tracers)
  6. Applications in mouse, rat and non-human primate circuits.
Size Custom
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Dry ice
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