Cathepsin K Activity Assay Kit

Name: Cathepsin K Activity Assay Kit
SKU: PTAK-018

For research use only. Not intended for any clinical use.

Cat.No.

PTAK-018

Description

The Cathepsin K Activity Assay kit is a fluorescence-based assay that utilizes the preferred cathepsin K substrate sequence LR
labeled with AFC (amino-4-trifluoromethyl coumarin). The cathepsin K assay is simple, straightforward, and can be adapted to 96-well plate assays. Assay conditions have been optimized to obtain the maximal activity.

Applications

Useful for detecting the activity of Cathepsin K

Caution

Avoid freeze/thaw cycles

Component

•Cathepsin K
•CTSK substrate (Ac-LR-AFC)
•Cathepsin assay buffer
•CTSK inhibitor

Method

Fluorescence

Size/Form

100 assays

Publications

Q & A

Customer Reviews

Customer Q&As

What is Cathepsin K？

A: Cathepsin K is a lysosomal cysteine protease that plays a key role in bone remodeling and turnover.

What is the function of cathepsin K?

A: The primary function of cathepsin K is to break down bone tissue by degrading collagen, elastin, and other proteins found in bones.

What does cathepsin K cleave?

A: Cathepsin K is a lysosomal cysteine protease that mainly cleaves type I collagen, which is the major structural protein in bones and connective tissues.

What methods are available to measure cathepsin K activity?

A: There are several methods available to measure cathepsin K activity, including fluorescence-based assays, colorimetric assays, and radiolabeled substrate assays.

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