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Rat P2ry12 Stable Cell Line-CHO dhfr-

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Cat.No.
CSC-RG0373
Background
P2RY12 or P2Y12 is a G-protein coupled receptor for ADP and ATP. ADT released from platelets acts in a positive feedback mechanism on P2Y12 and P2Y1 on platelets and is critical for sustained aggregation and stabilization of thrombin. P2Y12 receptor plays a central role in platelet activation and is the target of of antithrombotic drugs such as ticlopidine and clopidogrel.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO dhfr-
Ship
Dry ice
Gene Information
Official Symbol
P2ry12
Synonyms
P2RY12; purinergic receptor P2Y, G-protein coupled, 12; P2Y purinoceptor 12; P2Y12 platelet ADP receptor; P2y12;
Gene ID
Pathway
ADP signalling through P2Y purinoceptor 12, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Hemostasis, organism-specific biosystem;
Function
ADP receptor activity; ADP receptor activity; G-protein coupled adenosine receptor activity; G-protein coupled adenosine receptor activity; receptor activity; signal transducer activity;

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