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HumanDRD1-tGFP Stable Cell Line-SHSY5Y

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Cat.No.
CSC-RG0036
Background
The gene encodes the D1 subtype of the Dopamine receptor. This subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. Dopamine is one of the most important neurotransmitters and the expression of its receptors is well characterized in brain.
Dopamine receptors are involved in many neurological processes so their abnormal signalling is implicated in several neuropsychiatric disorders. DRD1 mediates some behavioural responses, regulates neuronal growth and development.
Growth Properties
Mixed, adherent and suspension
Morphology
Epithelial
Host Cell
SHSY5Y
Ship
Dry ice
Gene Information
Official Symbol
DRD1
Synonyms
DRD1; dopamine receptor D1; D(1A) dopamine receptor; dopamine D1 receptor; DADR; DRD1A;
Gene ID
MIM
UniProt ID
P21728
Chromosome Location
5q34-q35
Pathway
Amine ligand-binding receptors, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cocaine addiction, organism-specific biosystem;
Function
G-protein coupled receptor activity; dopamine binding; dopamine receptor activity; dopamine receptor activity, coupled via Gs; dopamine receptor activity, coupled via Gs; drug binding; protein binding; receptor activity; signal transducer activity;

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