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Human XCR1 Validated Stable Cell Line-CHO

See other products for XCR1
Cat.No.
CSC-RG1148
Background
The migration of leukocytes from the bloodstream to sites of inflammation is a dynamic factor involving adhesion molecules and chemotactic factors. Chemokines play a role in the trafficking of leukocytes by inducing cellular motility and activating adhesion molecules within the immune system. Lymphotactin (also known as XCL1 and SCM-1) is a unique chemokine that retains only two of the four cysteine residues found in the CC, CXC and CX3C families of chemokines. A Gi-coupled receptor, XCR1, binds to lymphotactin and mediates its chemotactic effects. Chemokines promote accumulation of activated mononuclear cells (MNCs) in inflamed joints in rheumatoid arthritis (RA) and lymphotacin is highly expressed in synovial fluid of RA patients. In situ hybridization studies indicate that XCR1 expression was detected in both the infiltrated MNCs and the synoviocytes from synovial specimens taken from RA patients.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
XCR1
Synonyms
XCR1; chemokine (C motif) receptor 1; CCXCR1, chemokine (C motif) XC receptor 1 , GPR5; chemokine XC receptor 1; lymphotactin receptor; XC chemokine receptor 1; G protein-coupled receptor 5; G-protein coupled receptor 5; chemokine (C motif) XC receptor 1; GPR5; CCXCR1;
Gene ID
MIM
UniProt ID
P46094
Chromosome Location
3p21.3-p21.1
Pathway
Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (q) signalling events, organism-specific biosystem;
Function
G-protein coupled receptor activity; chemokine receptor activity; receptor activity; signal transducer activity;
Related Products
Cat#
Product Name
Host Cell
Gene Symbol
Species
Price
CSC-RG0520
CHO-K1
XCR1
Human
Cat#
Product Name
Titer
Product Size
Species
Price
AD17819Z
>1x 10^9 vp/ml
1 x 0.2 ml
Human

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45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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