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Rat Xcr1 cDNA Clone(NM_001106871.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006599

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Gene Information

Cat. No. CDFR006599
Description NativeORF clone of Rattus norvegicus chemokine (C motif) receptor 1 (Xcr1) as transfection-ready DNA NM_001106871.1
Product Type cDAN Clone
Gene Abbr Xcr1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene XCR1
Background The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains. The encoded protein transduces a signal by increasing the intracellular calcium ion level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Some studies have implicated a cluster of genes at 3p21.31, including this gene, as associated with COVID-19 risk. The encoded protein may also play a role in cell proliferation and migration in several types of cancer. [provided by RefSeq, Jan 2023]
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