Human TLR1 Stable Cell Line-HEK293T

Name: Human TLR1 Stable Cell Line-HEK293T
SKU: CSC-RO0053
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RO0053

Host Cell : HEK293T Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RO0053
Description	This cell line is a stably transfected cell line which expresses human Toll-like receptor 1 (TLR1) with an N-terminal HA tag.
Background	The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes.
Target Gene	TLR1
Gene Species	Homo sapiens (Human)
Host Cell	HEK293T
Host Cell Species	Homo sapiens (Human)
Source	HEK293
Applications	1. Studying the interactions between immune cells and cancer cells 2. Studying the mechanisms of resistance to immune checkpoint blockade 3. High-throughput screening 4. Drug target validation
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TLR1 toll like receptor 1 [ Homo sapiens (human) ]
Gene Symbol	TLR1
Synonyms	TIL; CD281; rsc786; TIL. LPRS5
GeneID	7096
Uni ProtID	Q15399
Chromosome Location	4p14

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Q & A

Customer Reviews

Customer Q&As

What is the host cell of Human TLR1 Stable Cell Line-HEK293 cell line?

A: The host cell of Human TLR1 Stable Cell Line-HEK293 cell line is HEK293 type cells.

Can Human TLR1 Stable Cell Line-HEK293 cell line be used for clinical research?

A: No, it's for research use only, not for any clinical purposes.

What is the function of the TLR1 gene?

A: The protein encoded by the TLR1 gene is a member of the Toll-like receptor (TLR) family and plays an important role in pathogen recognition and innate immune activation.

Is the TLR1 gene conserved?

A: Yes, from fruit flies to humans, TLRs are highly conserved with structural and functional similarities.

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