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Human TLR1 Stable Cell Line-HEK293

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Cat.No.
CSC-RO0053
Cell Line Description
This cell line is a stably transfected cell line which expresses human Toll-like receptor 1 (TLR1) with an N-terminal HA tag.
Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes.
Host Cell
HEK293
Ship
Dry ice
Antigen Gene Information
Official Symbol
TLR1
Synonyms
TIL; CD281; rsc786; TIL. LPRS5
GeneID
UniProt ID
Q15399
Chromosome Location
4p14

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