Cynomolgus TLR1 ORF clone

Name: Cynomolgus TLR1 ORF clone
SKU: CDCB156619
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCB156619

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Product Information

Gene Information

Cat. No.	CDCB156619
Description	ORF Clone of Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) toll-like receptor 1 DNA. Identical with XM_001085890.2 [ Macaca mulatta (Rhesus monkey) ]:409 A/G, 820 T/C, 986 A/G, 1393 A/G resulting in the amino acid Asn substitution by Asp, Trp substitution by Arg, Lys substitution by Thr, Ile substitution by Val and 1875 T/C, 1890 A/G, 2313 C/T not causing the amino acid variation.
Gene Abbr	TLR1
Species	Cynomolgus
ORF Size	2361 bp
Sequence	ATGACTAGCA TCTTCCATTT TGCCATTATC TTTATGTTAA CACTTCAGAT CAGAATACAA TTATCTGAAG AAAGTGAATT TTTAGTTGAT AGGTCAAAAA ACAGTCTCAT CCACGTTCCT AAAGACCTAT CCCAGAAAAC AACAATCTTA AATATATCAC AAAATTATAT ATCTGAGCTT TGGACTTCTG ACATCTTATC ACTGTCAAAG CTGAGGATTT TGATAATTTC TCATAATAGA CTCCAGTATC TTGATATCAG TGTTTTCAAA TTCAACCAGG AATTGGAATA CTTGGATTTG TCCCACAACA AGTTGGCGAA AATTTCTTGC CACCCTACTG TGAACCTCAA GCACTTGGAC CTGTCCTTTA ATGCATTTGA TGCCCTGCCT ATATGCAAAG AGTTTGGCGA TATGTCTCAA CTAAAATTTC TGGGGTTGAG CACTACACAC TTAGAAAAAT CTACTGTGCT GCCAATTGCT CATTTGAATA TCAGCAAGGT CTTGCTGGTC TTAGGAGAGC ATTATGGGGA CAAAGAAGAC CCTGAGGGCC TTCAAAACTT TAACACTGAG AGTCTGCACA TTGTGTTCCC AACAAGCAAA GAATTCAATT TTATTTTGGA TGTGTCAGTC AGGACTGTAG CAAATCTGGA ACTATCTAAT ATCAAATGTG TGCTAGAAGA TAACGAATGT TCTTACTTCC TAAATATTCT GGCAAAACTT CAAACAAATC CAAAGTTATC AAGTCTTACT TTAAACAACA TTGAAACAAC TTGGAATTCT TTCATTAGGA TCCTCCAGCT GGTTTGGCAT ACAACCGTAC GGTATTTCTC AATTTCAAAC GTGAAGCTAC AGGGTCAACT GGACTTCAGA GATTTTGATT ATTCTGGCAC TTCCCTGAAG GCCTTGTCTG TACACCAAGT CGTCAGCGAT GTGTTCAATT TTCCACAAAG GGATATCTAT GAAATCTTTT CAAATATGAA CATCAGAAAT TTCACAGTGT CTGGTACACG CATGATCCAC ATGGTTTGCC CATCCAAAAT CAGCCCGTTC CTGCATTTGG ATTTTTCCAA TAATCTCTTA ACAGACACGG TTTTTGAAAA TTGTGGGCAC CTTACTGAGT TGGAGACACT TATTTTACAA ATGAATCAAT TAAAAGAACT TTCAAAAATA GCTGAAATGA CTACACGGAT GAAGTCTCTG CAACAATTGG ATATTAGCCA GAATTCTGTA AGCTATGATG AAAAGAAAGG AGATTGCTCT TGGACTAAAA GTTTATTAAG TTTAAATATG TCTTCAAATA TACTTACTGA CACTATTTTC AAATGTTTAC CTCCCAGGAT CAAGGTACTT GATCTTCACA GCAATAAAAT AAAGAGCATT CCTAAACAAG TCGTAAAACT GGAAGCTTTG CAAGAACTCA ATGTTGCTTT CAATTCTTTA ACTGACCTTC CTGGATGTGG CAGCTTTAGC AGCCTTTCTG TATTGATCAT TGATCACAAT TCAGTTTCCC ACCCATCAGC TGATTTCTTC CAGAGCTGCC AGAAGATGAG GTCAATAAAA GCAGGGAACA ATCCATTCCA GTGTACCTGT GAGCTAAGAG AATTTGTCAA AAATATAGAG CAAGTATCAA GTGAAGTGGT AGAGGGCTGG CCTGATTCTT ATAAGTGTGA CTACCCAGAA AGTTATAGAG GAACCCCACT AAAGGACTTT CACATGTCTG AATTATCCTG CAACATAACT CTGCTGATCG TCACCATCGG TGCCACCATG CTGGTGTTGG CTGTGACTGT GACCTTCCTC TGCATCTACT TGGATCTGCC CTGGTATCTC AGGATGGTGT GCCAGTGGAC CCAGACCCGG CGCAGGGCCA GGAACGTACC CTTAGAAGAG CTCCAAAGAA ATCTCCAGTT TCATGCATTT ATTTCATATA GTGGGCACGA TTCTTTCTGG GTGAAGAATG AATTATTACC AAACCTAGAG AAAGAAGGTA TGCAGATTTG CCTTCATGAG AGAAACTTTG TTCCTGGCAA GAGCATTGTG GAAAATATCA TCAACTGCAT TGAGAAGAGT TACAAGTCCA TCTTTGTTTT GTCTCCCAAC TTTGTCCAGA GTGAGTGGTG CCATTATGAA CTCTACTTTG CCCATCACAA TCTCTTTCAT GAAGGATCTA ATAACTTAAT CCTGATCTTG CTGGAACCCA TTCCGCAGTA CTCCATTCCT AGCAGCTATC ACAAGCTCAA AAATCTCATG GCCAGGAGGA CTTATTTGGA ATGGCCCAAG GAAAAGAGCA AACATGGGCT TTTTTGGGCT AATCTAAGGG CAGCCATTAA TATTAAGCTG ACAGAGCAAG CAAAAAAATA G

Target Gene

TLR1

Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq, Jul 2008]

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