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Human PTH1R Stable Cell Line-HEK293T

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Cat.No.
CSC-RG1744
Background
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis.
Host Cell
HEK293T
Ship
Dry ice
Antigen Gene Information
Official Symbol
PTH1R
Synonyms
PFE; PTHR; PTHR1
GeneID
MIM
UniProt ID
Q03431
Chromosome Location
3p22-p21.1
Pathway
Class B/2 (Secretin family receptors), organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, organism-specific biosystem; Endocrine and other factor-regulated calcium reabsorption, conserved biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem;
Function
parathyroid hormone receptor activity; peptide hormone binding; protein self-association;

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