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Human PRLHR Stable Cell Line-CHO dhfr-

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-RG0358

Host Cell :   CHO dhfr- Size :   >1x106 frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No. CSC-RG0358
Background Prolactin-releasing peptide receptor PRRP (or GPR10) is detected in human brain, pituitaries, normal portions of adrenal glands and various tumor tissues. High level of expression is detected in pheochromocytomas. GPR10 was investigated regarding the effect of normal and high-fat diets on energy intake, body weight, and glucose homeostasis in wild-type and GPR10 knockout mice. The investigation provided direct evidence that GPR10 is involved in the regulation of energy balance.
Target Gene PRLHR
Gene Species Homo sapiens (Human)
Abbr CHO dhfr--HuPRLHR
Alias PRLHR, GPR10, hGR3, GR3, PrRPR, MGC126539, MGC126541
Host Cell CHO dhfr-
Host Cell Species Cricetulus griseus (Chinese hamster)
Applications

1. Gene expression studies

2. Signaling pathway research

3. Drug screening and toxicology

4. Research on the mechanisms of GPCR-related diseases

Size >1x106 frozen cells/vial
Stability Validated for at least 10 passages
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid nitrogen
Shipping Dry ice
Revival Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties Adherent
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name PRLHR prolactin releasing hormone receptor [ Homo sapiens ]
Gene Symbol PRLHR
Synonyms GR3; GPR10; PrRPR
Gene Description prolactin releasing hormone receptor
Gene ID 2834
Uni Prot ID A5JUU5
m RNA Refseq NM_004248.2
Protein Refseq NP_004239.1
Chromosome Location 10q26.13
Function G-protein coupled receptor activity; neuropeptide Y receptor activity; neuropeptide receptor activity; peptide hormone binding;
Pathway Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem; Peptide ligand-binding receptors, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
MIM 600895
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