Cat.No. : CSC-RG1639 Host Cell: 1321N1
| Cat. No. | CSC-RG1639 |
| Background | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP. |
| Gene | P2RY4 |
| Gene Species | Homo sapiens (Human) |
| Host Cell | 1321N1 |
| Species | Homo sapiens (Human) |
| Stability | Validated for at least 10 passages |
| Application | 1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases |
| Quality Control | Negative for bacteria, yeast, fungi and mycoplasma. |
| Shipping | Dry Ice |
| Storage | Liquid nitrogen |
| Source | 1321N1 |
| Subgroup | Human |
| Revival | Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media. |
| Gene Name | P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 [ Homo sapiens ] |
| Gene Symbol | P2RY4 |
| Synonyms | NRU; P2P; UNR; P2Y4 |
| Gene Description | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| Gene ID | 5030 |
| UniProt ID | P51582 |
| mRNA Refseq | NM_002565.3 |
| Protein Refseq | NP_002556.1 |
| Chromosome Location | Xq13 |
| Pathway | Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem; |
| MIM | 300038 |
| Mycoplasma | Negative |
| Format | One frozen vial containing millions of cells |
| Storage | Liquid nitrogen |
| Safety Considerations |
The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach. |
| Ship | Dry ice |
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