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Human HTR3A Stable Cell Line-HEK293

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Cat.No.
CSC-RI0059
Background
The human HTR3A gene encodes the pore-forming subunit of 5-HT3A, a ligand-gated cation channel activated by 5-hydroxytryptamine (serotonin). 5-HT3A channels expressed in the CNS and GI tract, are therapeutic targets in nausea and irritable bowel syndrome.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
HTR3A
Synonyms
HTR3A; 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic; 5 hydroxytryptamine (serotonin) receptor 3A , HTR3; 5-hydroxytryptamine receptor 3A; 5 HT3A; 5 HT3R; 5-HT3-A; serotonin receptor 3A; 5HT3 serotonin receptor; 5-hydroxytryptamine receptor 3; serotonin-gated ion channel receptor; HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R;
Gene ID
MIM
UniProt ID
P46098
Chromosome Location
11q23.1-q23.2
Pathway
Ion channel transport, organism-specific biosystem; Ligand-gated ion channel transport, organism-specific biosystem; Serotonergic synapse, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem;
Function
extracellular ligand-gated ion channel activity; extracellular ligand-gated ion channel activity; ion channel activity; receptor activity; serotonin binding; serotonin receptor activity; serotonin receptor activity; serotonin-activated cation-selective channel activity;

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