Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CSC-RG0296
Host Cell : CHO dhfr- Size : >1x106 frozen cells/vial
| Cat. No. | CSC-RG0296 |
| Background | Melanin-concentrating hormone receptor 2 (MCHR2, or GPR145) is the second MCH receptor identified in human. The primary function of both MCH receptors, MCHR1 and MCHR2, is to regulate skin color. In addition, they also regulate food intake, energy expenditure, behavior and emotion. |
| Target Gene | MCHR1 |
| Abbr | CHO dhfr--HuMCHR2 |
| Alias | MCHR1, GPR24, MCH1R, SLC1, SLC-1, MCH-1R, MGC32129 |
| Host Cell | CHO dhfr- |
| Host Cell Species | Cricetulus griseus (Chinese hamster) |
| Applications |
1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases |
| Size | >1x106 frozen cells/vial |
| Stability | Validated for at least 10 passages |
| Quality Control | Negative for bacteria, yeast, fungi and mycoplasma. |
| Storage | Liquid nitrogen |
| Shipping | Dry ice |
| Revival | Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media. |
| Growth Properties | Adherent |
| Mycoplasma | Negative |
| Format | One frozen vial containing millions of cells |
| Storage | Liquid nitrogen |
| Safety Considerations |
The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach. |
| Ship | Dry ice |
| Gene Name | MCHR1 melanin-concentrating hormone receptor 1 [ Homo sapiens ] |
| Gene Symbol | MCHR1 |
| Synonyms | SLC1; GPR24; MCH1R |
| Gene Description | melanin-concentrating hormone receptor 1 |
| Gene ID | 2847 |
| Uni Prot ID | Q99705 |
| m RNA Refseq | NM_005297.3 |
| Protein Refseq | NP_005288.3 |
| Chromosome Location | 22q13.2 |
| Function | G-protein coupled receptor activity; hormone binding; melanin-concentrating hormone receptor activity; neuropeptide receptor activity; protein C-terminus binding; |
| Pathway | Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Gastrin-CREB signalling pathway via PKC and MAPK, organism-specific biosystem; |
| MIM | 601751 |
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