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Human KCNQ2/KCNQ3 Stable Cell Line-CHO

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Cat.No.
CSC-RI0043
Background
Kv7.2 and Kv7.3 are both voltage-gated, delayed rectifier potassium channels. Together they co assemble to form the M current in the brain. The M current is a slowly activating and deactivating potassium conductance that plays a crucial role in determining the excitability of neurons as well as their responsiveness to synaptic inputs. This current is also expressed in many neurons in the central nervous system. Enhancers of the M current are used for antiepileptic therapy and blockers have been shown to enhance learning and memory.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
KCNQ3
Synonyms
KCNQ3; potassium voltage-gated channel, KQT-like subfamily, member 3; EBN2; potassium voltage-gated channel subfamily KQT member 3; Kv7.3; potassium channel subunit alpha KvLQT3; voltage-gated potassium channel subunit Kv7.3; potassium channel, voltage-gated, subfamily Q, member 3; BFNC2; KV7.3; FLJ37386; FLJ38392; DKFZp686C0248;
Gene ID
MIM
UniProt ID
O43525
Chromosome Location
8q24
Pathway
Axon guidance, organism-specific biosystem; Cholinergic synapse, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Interaction between L1 and Ankyrins, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem;
Function
potassium channel activity; voltage-gated ion channel activity; voltage-gated potassium channel activity;
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Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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