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Human KCNC2 Stable Cell Line-CHO

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Cat.No.
CSC-RI0038
Background
Kv3.2 channels are expressed in neurons known to fire at high frequency. Their biophysical properties could enable cells to generate the fast chains of action potentials involved in neuronal excitability. They are thought to play a role in the regulation of the human 24hr circadian rhythm, as they are highly expressed in the suprachiasmatic nucleus. Kv3.2 channels are also found in the insulin secreting beta-cells of the pancreas and their modulation could provide novel targets in the treatment of type-2 diabetes.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
KCNC2
Synonyms
KCNC2; potassium voltage-gated channel, Shaw-related subfamily, member 2; potassium voltage-gated channel subfamily C member 2; Kv3.2; voltage-gated potassium channel Kv3.2; KV3.2; MGC138196;
Gene ID
MIM
UniProt ID
Q96PR1
Chromosome Location
12q14.1
Pathway
Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Regulation of Insulin Secretion, organism-specific biosystem; Regulation of Insulin Secretion by Glucagon-like Peptide-1, organism-specific biosystem; Voltage gated Potassium channels, organism-specific biosystem;
Function
voltage-gated ion channel activity; voltage-gated potassium channel activity;

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