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Human KCNC1 Stable Cell Line-CHO

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Cat.No.
CSC-RI0037
Background
Kv3.1 mRNA is abundantly expressed in auditory brain stem neurons that are able to spike at high frequencies. It has a high threshold of activation and rapid activation/deactivation kinetics. Evidence for functional Kv3.1 activity in such neurons can be derived from the rapidly activating and deactivating potassium currents seen here, that activate at a high-voltage threshold similar to that of heterologously expressed Kv3.1. There are indications that the phosphorylation state in rat Kv3.1 may play a part in the ability of auditory neurons to adjust to the ambient acoustic environment. It is thought that Kv3.1 subunits are likely to form homomultimers in lymphocytes and therefore could be a target for the development of novel immunosuppresants.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
KCNC1
Synonyms
KCNC1; potassium voltage-gated channel, Shaw-related subfamily, member 1; potassium voltage-gated channel subfamily C member 1; Kv3.1; voltage-gated potassium channel subunit Kv4; voltage-gated potassium channel protein KV3.1; voltage-gated potassium channel subunit Kv3.1; KV4; NGK2; KV3.1; FLJ41162; FLJ42249; FLJ43491; MGC129855;
Gene ID
MIM
UniProt ID
P48547
Chromosome Location
11p15
Pathway
Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Voltage gated Potassium channels, organism-specific biosystem;
Function
voltage-gated ion channel activity; voltage-gated potassium channel activity;

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