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Human CACNA1C/CACNB2/CACNA2D1 Stable Cell Line-CHO

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Cat.No.
CSC-RI0068
Background
The human CACNA1C gene encodes the pore-forming subunits of Cav1.2. CACNB2 and CACNA2D1 encode auxiliary subunits that modulate gating and pharmacological properties. Cav1.2 channels expressed in heart, smooth muscle, neurons, and endocrine tissue are therapeutic targets in cardiac arrhythmia and hypertension.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO
Ship
Dry ice
Gene Information
Official Symbol
CACNB2
Synonyms
CACNB2; calcium channel, voltage-dependent, beta 2 subunit; CACNLB2, MYSB; voltage-dependent L-type calcium channel subunit beta-2; CAB2; lambert-Eaton myasthenic syndrome antigen B; myasthenic (Lambert-Eaton) syndrome antigen B; calcium channel voltage-dependent subunit beta 2; MYSB; CAVB2; CACNLB2; FLJ23743;
Gene ID
MIM
UniProt ID
Q08289
Chromosome Location
10p12
Pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Axon guidance, organism-specific biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels, organism-specific biosystem; Developmental Biology, organism-specific biosystem;
Function
calcium channel activity; calcium channel regulator activity; protein binding; voltage-gated calcium channel activity; voltage-gated ion channel activity;

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