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Human CACNA1B/CACNB3/CACNA2D1 Stable Cell Line-CHO

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Cat.No.
CSC-RI0075
Background
The human CACNA1B gene encodes the pore-forming subunit of Cav2.2, the voltage-gated N-type calcium channel. CACNB3 and CACNA2D1 encode auxiliary subunits that modulate gating and pharmacological properties. Cav2.2 channels expressed in CNS neurons are therapeutic targets in pain.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO
Ship
Dry ice
Gene Information
Official Symbol
CACNB3
Synonyms
CACNB3; calcium channel, voltage-dependent, beta 3 subunit; CACNLB3; voltage-dependent L-type calcium channel subunit beta-3; CAB3; FLJ58949;
Gene ID
MIM
UniProt ID
P54284
Chromosome Location
12q13
Pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Axon guidance, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels, organism-specific biosystem;
Function
contributes_to voltage-gated calcium channel activity; voltage-gated ion channel activity;

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