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shRNA set against Rat Pten(NM_031606.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHR150040

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Product Information

Gene Information

Cat. No. SHR150040
Description Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr Pten
Gene Name Pten phosphatase and tensin homolog [ Rattus norvegicus ]
Species Rat
Content Each set contains 4 shRNA expression constructs.
Promoter H1
Selection Marker Puromycin
Format 5 μg purified plasmid
Unit Size 5 μg
Gene Name Pten phosphatase and tensin homolog [ Rattus norvegicus ]
Gene Symbol Pten
Synonyms Mmac; TEP1; MMAC1
Gene Description phosphatase and tensin homolog
Gene ID 50557
Uni Prot ID O54857
m RNA Refseq NM_031606.1
Protein Refseq NP_113794.1
Chromosome Location 1q41-q43
Function PDZ domain binding; PDZ domain binding; anaphase-promoting complex binding; enzyme binding; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; phosphatidylinositol-3-phosphatase activity; phosphoprotein phosphatase activity; platelet-derived growth factor receptor binding; protein binding; protein kinase binding; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity;
Pathway Adaptive Immune System, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Constitutive PI3K/AKT Signaling in Cancer, organism-specific biosystem; DAP12 interactions, organism-specific biosystem; DAP12 signaling, organism-specific biosystem; Disease, organism-specific biosystem; Downstream Signaling Events Of B Cell Receptor (BCR), organism-specific biosystem;
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