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shRNA set against Rat PTEN (NM_031606.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH385916

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Gene Information

Cat. No. SHH385916
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr PTEN
Gene Name Pten phosphatase and tensin homolog [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Pten phosphatase and tensin homolog [ Mus musculus ]
Gene Symbol Pten
Synonyms TEP1; MMAC1; AI463227; 2310035O07Rik; A130070J02Rik; B430203M17Rik
Gene Description phosphatase and tensin homolog
Gene ID 19211
Uni Prot ID O08586
m RNA Refseq NM_008960.2
Protein Refseq NP_032986.1
Chromosome Location 19 C1; 19 24.5 cM
Function PDZ domain binding; anaphase-promoting complex binding; enzyme binding; hydrolase activity; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; magnesium ion binding; phosphatase activity; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; phosphatidylinositol-3-phosphatase activity; phosphoprotein phosphatase activity; platelet-derived growth factor receptor binding; protein binding; protein kinase binding; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity;
Pathway Adaptive Immune System, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Constitutive PI3K/AKT Signaling in Cancer, organism-specific biosystem; DAP12 interactions, organism-specific biosystem; DAP12 signaling, organism-specific biosystem; Disease, organism-specific biosystem; Downstream Signaling Events Of B Cell Receptor (BCR), organism-specific biosystem;
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