shRNA set against Human PTEN(NM_000314.4)

Name: shRNA set against Human PTEN(NM_000314.4)
SKU: SHR150132
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHR150132

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Product Information

Gene Information

Cat. No.	SHR150132
Description	Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr	PTEN
Gene Name	PTEN phosphatase and tensin homolog [ Homo sapiens ]
Species	Human
Report Gene	eGFP
Content	Each set contains 4 shRNA expression constructs.
Promoter	H1
Selection Marker	Puromycin
Format	5 μg purified plasmid
Unit Size	5 μg

Gene Name	PTEN phosphatase and tensin homolog [ Homo sapiens ]
Gene Symbol	PTEN
Synonyms	BZS; DEC; GLM2; MHAM; TEP1; MMAC1; PTEN1; 10q23del
Gene Description	phosphatase and tensin homolog (mutated in multiple advanced cancers 1)
Gene ID	5728
Uni Prot ID	F6KD01
m RNA Refseq	NM_000314.4
Protein Refseq	NP_000305.3
Chromosome Location	10q23.3
Function	PDZ domain binding; anaphase-promoting complex binding; enzyme binding; inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; lipid binding; magnesium ion binding; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; phosphatidylinositol-3-phosphatase activity; phosphoprotein phosphatase activity; protein binding; protein kinase binding; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity;
Pathway	3-phosphoinositide degradation, organism-specific biosystem; 3-phosphoinositide degradation, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem; Class I PI3K signaling events, organism-specific biosystem; Constitutive PI3K/AKT Signaling in Cancer, organism-specific biosystem;
MIM	601728

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