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shRNA set against Mouse Tlr4(NM_021297.2)

Cat.No.
SHR166854
Description
Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Content
Each set contains 4 shRNA expression constructs.
Format
5 μg purified plasmid
Promoter
H1
Report Gene
eGFP
Selection Marker
Puromycin
Species
Mouse
Unit Size
5 μg
Gene Information
Gene Symbol
Tlr4
Synonyms
Lps; Ly87; Ran/M1; Rasl2-8
Gene Description
toll-like receptor 4
Gene ID
UniProt ID
Q9QUK6
mRNA Refseq
Protein Refseq
Chromosome Location
4 C1; 4 33.0 cM
Function
lipopolysaccharide binding; lipopolysaccharide receptor activity; phosphatidylinositol 3-kinase binding; protein binding; receptor activity; transmembrane signaling receptor activity;
Pathway
Activated TLR4 signalling, organism-specific biosystem; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; HIF-1 signaling pathway, organism-specific biosystem;

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