shRNA set against Human TLR4 (NM_138554.4)

Name: shRNA set against Human TLR4 (NM_138554.4)
SKU: SHH427984
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH427984

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Gene Information

Cat. No.	SHH427984
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	TLR4
Gene Name	TLR4 toll-like receptor 4 [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	TLR4 toll-like receptor 4 [ Homo sapiens ]
Gene Symbol	TLR4
Synonyms	TLR4; toll-like receptor 4; CD284; hToll; TLR 4; homolog of Drosophila toll; TOLL; TLR-4; ARMD10;
Gene ID	7099
Uni Prot ID	O00206
m RNA Refseq	BC117422
Chromosome Location	9q33.1
Function	lipopolysaccharide binding; lipopolysaccharide binding; lipopolysaccharide receptor activity; phosphatidylinositol 3-kinase binding; protein binding; receptor activity; transmembrane signaling receptor activity;
Pathway	Activated TLR4 signalling, organism-specific biosystem; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; IKK complex recruitment mediated by RIP1, organism-specific biosystem;

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