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shRNA set against Human FLT3 (NM_004119.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH295769

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Gene Information

Cat. No. SHH295769
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr FLT3
Gene Name FLT3 fms-related tyrosine kinase 3 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name FLT3 fms-related tyrosine kinase 3 [ Homo sapiens ]
Gene Symbol FLT3
Synonyms FLK2; STK1; CD135; FLK-2
Gene Description fms-related tyrosine kinase 3
GeneID 2322
Uni ProtID P36888
mRNA Refseq NM_004119.2
Protein Refseq NP_004110.2
Chromosome Location 13q12
Function ATP binding; cytokine receptor activity; phosphatidylinositol 3-kinase binding; protein binding; protein homodimerization activity; transmembrane receptor protein tyrosine kinase activity; vascular endothelial growth factor-activated receptor activity;
Pathway Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Pathways in cancer, organism-specific biosystem;
MIM 136351
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