Human LILRB3 Stable Cell Line - CHO-K1

Name: Human LILRB3 Stable Cell Line - CHO-K1
SKU: CSC-RO0935
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RO0935

Host Cell : CHO-K1 Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RO0935
Description	This cell line is engineered to stably overexpress human LILRB3.
Target Gene	LILRB3
Gene Species	Homo sapiens (Human)
Host Cell	CHO-K1
Host Cell Species	Cricetulus griseus (Chinese hamster)
Applications	1. Studying the interactions between immune cells and cancer cells 2. Studying the mechanisms of resistance to immune checkpoint blockade 3. High-throughput screening 4. Drug target validation
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 [ Homo sapiens ]
Gene Symbol	LILRB3
Synonyms	HL9; ILT5; LIR3; PIRB; CD85A; ILT-5; LIR-3; LILRA6
Gene Description	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
Gene ID	11025
Uni Prot ID	O75022
m RNA Refseq	NM_006864.2
Protein Refseq	NP_006855.2
Chromosome Location	19q13.4
Function	protein binding; receptor activity; transmembrane signaling receptor activity;
Pathway	Adaptive Immune System, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem;
MIM	604820

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Q & A

Customer Reviews

Customer Q&As

How was the Human CLEC9A Stable Cell Line - CHO-K1 constructed?

A: It was developed by transfecting the human CLEC9A gene into Chinese hamster ovary cells (CHO-K1) using genetic engineering techniques to achieve stable expression of the CLEC9A gene.

What are the primary research uses of the Human CLEC9A Stable Cell Line - CHO-K1?

A: It is primarily used to study the role of CLEC9A in antigen capture, cross-presentation, and immune responses, especially in the research of tumor immunology and infectious diseases.

What special considerations are there when culturing the Human CLEC9A Stable Cell Line - CHO-K1?

A: It should be cultured under aseptic conditions, maintaining appropriate temperature and pH levels, and regularly monitoring cell status and CLEC9A expression levels.

How is the Human CLEC9A Stable Cell Line - CHO-K1 used in immunotherapy research?

A: It can be used to test and develop immunotherapeutic drugs targeting CLEC9A, such as monoclonal antibodies for tumor immune responses.

What is the importance of the Human CLEC9A Stable Cell Line - CHO-K1 in cellular biology research?

A: Given the significance of CLEC9A in immune cell activation and tumor cell recognition, this cell line is crucial for studying its molecular mechanisms and signaling pathways.

How is the Human CLEC9A Stable Cell Line - CHO-K1 applied in disease model research?

A: It can be used to establish in vitro models of tumor immune responses and infectious diseases to study CLEC9A-mediated cellular immune responses.

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