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Human P2RY11 Stable Cell Line-1321N1 astrocytoma

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-RG0914

Host Cell :   1321N1 Size :   >1x106 frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No. CSC-RG0914
Background The human P2Y family of metabotropic receptors include eight accepted members, including P2Y1,2,4,6,11,12,13,14. P2Y2,4,11 are activated mainly by nucleoside triphosphates whereas P2Y1,6,12,13 are activated by nucleoside diphosphates. P2Y11 couples both to Gq/11 and to Gs and is expressed in a variety of tissues including epithelia, smooth muscle, granulocytes, dendritic cells and kidney.
Target Gene P2RY11
Gene Species Homo sapiens (Human)
Abbr 1321N1 astrocytoma-HuP2RY11
Alias P2RY11, P2Y11
Host Cell 1321N1
Host Cell Species Homo sapiens (Human)
Applications

1. Gene expression studies

2. Signaling pathway research

3. Drug screening and toxicology

4. Research on the mechanisms of GPCR-related diseases

Size >1x106 frozen cells/vial
Stability Validated for at least 10 passages
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid nitrogen
Shipping Dry ice
Revival Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties Adherent
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name P2RY11 purinergic receptor P2Y, G-protein coupled, 11 [ Homo sapiens ]
Gene Symbol P2RY11
Synonyms P2RY11; purinergic receptor P2Y, G-protein coupled, 11; P2Y purinoceptor 11; P2Y11; purinergic receptor P2Y11;
Gene ID 5032
Uni Prot ID Q96G91
m RNA Refseq BC073827
Chromosome Location 19p13.2
Function ATP-activated nucleotide receptor activity; G-protein coupled purinergic nucleotide receptor activity; G-protein coupled receptor activity; neurotransmitter receptor activity; receptor activity; signal transducer activity;
Pathway Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem;
MIM 602697
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