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Human P2RY11 Stable Cell Line-1321N1 astrocytoma

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Cat.No.
CSC-RG0914
Background
The human P2Y family of metabotropic receptors include eight accepted members, including P2Y1,2,4,6,11,12,13,14. P2Y2,4,11 are activated mainly by nucleoside triphosphates whereas P2Y1,6,12,13 are activated by nucleoside diphosphates. P2Y11 couples both to Gq/11 and to Gs and is expressed in a variety of tissues including epithelia, smooth muscle, granulocytes, dendritic cells and kidney.
Growth Properties
Adherent
Morphology
Glial
Host Cell
1321N1 astrocytoma
Stability
12 passages (6 weeks of continuous culture)
Ship
Dry ice
Gene Information
Official Symbol
P2RY11
Synonyms
P2RY11; purinergic receptor P2Y, G-protein coupled, 11; P2Y purinoceptor 11; P2Y11; purinergic receptor P2Y11;
Gene ID
MIM
UniProt ID
Q96G91
Chromosome Location
19p13.2
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem;
Function
ATP-activated nucleotide receptor activity; G-protein coupled purinergic nucleotide receptor activity; G-protein coupled receptor activity; neurotransmitter receptor activity; receptor activity; signal transducer activity;

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