Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CSC-RG0914
Host Cell : 1321N1 Size : >1x106 frozen cells/vial
| Cat. No. | CSC-RG0914 |
| Background | The human P2Y family of metabotropic receptors include eight accepted members, including P2Y1,2,4,6,11,12,13,14. P2Y2,4,11 are activated mainly by nucleoside triphosphates whereas P2Y1,6,12,13 are activated by nucleoside diphosphates. P2Y11 couples both to Gq/11 and to Gs and is expressed in a variety of tissues including epithelia, smooth muscle, granulocytes, dendritic cells and kidney. |
| Target Gene | P2RY11 |
| Gene Species | Homo sapiens (Human) |
| Abbr | 1321N1 astrocytoma-HuP2RY11 |
| Alias | P2RY11, P2Y11 |
| Host Cell | 1321N1 |
| Host Cell Species | Homo sapiens (Human) |
| Applications |
1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases |
| Size | >1x106 frozen cells/vial |
| Stability | Validated for at least 10 passages |
| Quality Control | Negative for bacteria, yeast, fungi and mycoplasma. |
| Storage | Liquid nitrogen |
| Shipping | Dry ice |
| Revival | Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media. |
| Growth Properties | Adherent |
| Mycoplasma | Negative |
| Format | One frozen vial containing millions of cells |
| Storage | Liquid nitrogen |
| Safety Considerations |
The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach. |
| Ship | Dry ice |
| Gene Name | P2RY11 purinergic receptor P2Y, G-protein coupled, 11 [ Homo sapiens ] |
| Gene Symbol | P2RY11 |
| Synonyms | P2RY11; purinergic receptor P2Y, G-protein coupled, 11; P2Y purinoceptor 11; P2Y11; purinergic receptor P2Y11; |
| Gene ID | 5032 |
| Uni Prot ID | Q96G91 |
| m RNA Refseq | BC073827 |
| Chromosome Location | 19p13.2 |
| Function | ATP-activated nucleotide receptor activity; G-protein coupled purinergic nucleotide receptor activity; G-protein coupled receptor activity; neurotransmitter receptor activity; receptor activity; signal transducer activity; |
| Pathway | Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; |
| MIM | 602697 |
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