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Human KCNN2 Stable Cell Line-CHO

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Cat.No.
CSC-RI0108
Background
The human KCNN2 gene encodes the pore-forming subunit of KCa2.2, the calcium-activated, voltage-gated SK2 potassium channel. KCa2 channels are responsible for afterhyperpolarization that regulates neuronal repetitive excitation. KCa2.2 channels expressed in CNS neurons are therapeutic targets in neurologic disorders (e.g., cognitive impairment and seizure).
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
KCNN2
Synonyms
KCNN2; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; small conductance calcium-activated potassium channel protein 2; hSK2; KCa2.2; SKCa 2; apamin-sensitive small-conductance Ca2+-activated potassium channel; SK2; SKCA2;
Gene ID
MIM
UniProt ID
Q9H2S1
Chromosome Location
5q22.3
Pathway
Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Ca2+ activated K+ channels, organism-specific biosystem; Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Serotonergic synapse, organism-specific biosystem;
Function
calmodulin binding; ion channel activity; potassium channel activity; small conductance calcium-activated potassium channel activity; small conductance calcium-activated potassium channel activity;

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