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Human HCN4 Stable Cell Line-HEK293

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Cat.No.
CSC-RI0102
Background
The human HCN4 gene encodes the pore-forming subunit of a hyperpolarization-activated, cyclic nucleotide-modulated cation channel. HCN4 channels are the predominant HCN isoform in the sinoatrial node and contribute to pacemaker current that controls rhythmic activity in the heart and brain. The HCN4 therapeutic potential includes treatment of cardiac arrhythmia and ischemic heart disease.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
HCN4
Synonyms
HCN4; hyperpolarization activated cyclic nucleotide-gated potassium channel 4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; hyperpolarization activated cyclic nucleotide-gated cation channel 4; SSS2;
Gene ID
MIM
UniProt ID
Q9Y3Q4
Chromosome Location
15q24.1
Pathway
HCN channels, organism-specific biosystem; Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem;
Function
cAMP binding; cation channel activity; intracellular cAMP activated cation channel activity; nucleotide binding; sodium channel activity; voltage-gated ion channel activity; voltage-gated potassium channel activity;

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