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Human CHRM3 Stable Cell Line-CHO

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Cat.No.
CSC-RG0060
Background
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
CHRM3
Synonyms
CHRM3; cholinergic receptor, muscarinic 3; muscarinic acetylcholine receptor M3; acetylcholine receptor; muscarinic 3; m3 muscarinic receptor; acetylcholine receptor, muscarinic 3; HM3; EGBRS;
Gene ID
MIM
UniProt ID
P20309
Chromosome Location
1q41-q44
Pathway
Amine ligand-binding receptors, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Cholinergic synapse, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem;
Function
G-protein coupled acetylcholine receptor activity; G-protein coupled receptor activity; acetylcholine binding; drug binding; phosphatidylinositol phospholipase C activity; receptor activity; signal transducer activity;

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