shRNA set against Human TP53(NM_001126116.1)

Name: shRNA set against Human TP53(NM_001126116.1)
SKU: SHL096420
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHL096420

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Product Information

Gene Information

Cat. No.	SHL096420
Description	Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr	TP53
Gene Name	TP53 tumor protein p53 [ Homo sapiens ]
Species	Human
Report Gene	eGFP
Content	Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence.
Promoter	H1
Selection Marker	Puromycin
Format	5 μg purified plasmid
Unit Size	5 μg
Sequence	The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Warning	This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	Store all tubes at -20 oC.
Shipping	Typically ships in 2-3 weeks

Gene Name	TP53 tumor protein p53 [ Homo sapiens ]
Gene Symbol	TP53
Synonyms	P53; BCC7; LFS1; TRP53
Gene Description	tumor protein p53 (Li-Fraumeni syndrome)
Gene ID	7157
Uni Prot ID	P04637
m RNA Refseq	NM_001126115.1
Protein Refseq	NP_001119587.1
Chromosome Location	17p13.1
Function	ATP binding; DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II transcription factor binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; chaperone binding; chromatin binding; copper ion binding; damaged DNA binding; enzyme binding; histone acetyltransferase binding; histone deacetylase regulator activity; identical protein binding; p53 binding; protease binding; protein N-terminus binding; protein binding; protein heterodimerization activity; protein kinase binding; protein phosphatase 2A binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding; ubiquitin protein ligase binding; zinc ion binding;
Pathway	AMPK signaling, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Activation of NOXA and translocation to mitochondria, organism-specific biosystem; Activation of PUMA and translocation to mitochondria, organism-specific biosystem; Alzheimers Disease, organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem;
MIM	191170

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