Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : MiUTR3H-02328
| Cat. No. | MiUTR3H-02328 |
| Description | 3'UTR clone of tumor protein p53 (TP53) transcript variant 3 for miRNA target validation |
| Gene Abbr | TP53 |
| Gene Name | TP53 tumor protein p53 [ Homo sapiens ] |
| Species | Human |
| Reporter | luciferase-RFP |
| Promoter | SV40 |
| Resistance | Neo/Kanr |
| Selection Marker | Neomycin |
| Size | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
| Vector | pMirTarget |
| Vector Type | plasmid |
| Storage | -20 ℃ |
| Gene Name | TP53 tumor protein p53 [ Homo sapiens ] |
| Gene Symbol | TP53 |
| Synonyms | P53; BCC7; LFS1; TRP53 |
| Gene Description | tumor protein p53 (Li-Fraumeni syndrome) |
| Gene ID | 7157 |
| Uni Prot ID | P04637 |
| m RNA Refseq | NM_001126115.1 |
| Protein Refseq | NP_001119587.1 |
| Chromosome Location | 17p13.1 |
| Function | ATP binding; DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II transcription factor binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; chaperone binding; chromatin binding; copper ion binding; damaged DNA binding; enzyme binding; histone acetyltransferase binding; histone deacetylase regulator activity; identical protein binding; p53 binding; protease binding; protein N-terminus binding; protein binding; protein heterodimerization activity; protein kinase binding; protein phosphatase 2A binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding; ubiquitin protein ligase binding; zinc ion binding; |
| Pathway | AMPK signaling, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Activation of NOXA and translocation to mitochondria, organism-specific biosystem; Activation of PUMA and translocation to mitochondria, organism-specific biosystem; Alzheimers Disease, organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; |
| MIM | 191170 |
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